. 2022 Aug 17;23(16):9224. doi: 10.3390/ijms23169224

Table 4.

A gene ontology (GO) enrichment analysis of secreted proteins downregulated in mPIN, MT and AT of prostate cancer.

mPIN Downregulated Gene Ontology (GO)
Pathway ID	Pathway Description	Gene Count	Adjusted p-Value	Log₁₀
GO:0062023	Collagen-containing extracellular matrix	6	0.000153	3.814225913
GO:0008237	Metallopeptidase activity	3	0.008113586	2.090787142
GO:0032027	Myosin light chain binding	1	0.049310437	1.307061149
GO:0008270	Zinc ion binding	3	0.049310437	1.307061149
MT Downregulated Gene Ontology (GO)
Pathway ID	Pathway Description	Gene Count	Adjusted p-Value	Log₁₀
GO:0062023	Collagen-containing extracellular matrix	7	0.0000450	4.34654643
GO:0005604	Basement membrane	2	0.037653103	1.424199233
GO:1903561	extracellular vesicle	2	0.037653103	1.424199233
AT Downregulated Gene Ontology (GO)
Pathway ID	Pathway Description	Gene Count	Adjusted p-Value	Log₁₀
GO:0062023	Collagen-containing extracellular matrix	6	0.000226	3.645111972
GO:0001823	Mesonephros development	2	0.028927408	1.538690472
GO:0004518	Nuclease activity	2	0.048024251	1.318539402
GO:0004540	Ribonuclease activity	2	0.048024251	1.318539402