Table 4.
Studies of DNA methyltransferases (DNMTs) and non-coding RNAs in cancer.
| ncRNAs | DNMT Deregulated in Cancer |
Type of Cancer | Type of Deregulation | Reference |
|---|---|---|---|---|
| DBCCR1-003 | DNMT1 | Bladder | Down | [145] |
| linc-POU3F3 | DNMT1, 3A, and 3B | ESCC | Up | [149] |
| miR-148a | DNMT1 | Gastric | Down | [150] |
| miR-29a | DNMT1 | Liver | Down | [151] |
| miR-152 | DNMT1 | Glioma | Down | [152] |
| miR-185 | DNMT1 | Glioma | Down | [153] |
| miR-145 | DNMT3A | Ovarian | Down | [144] |
| miR-101 | DNMT3A | Glioma | Down | [154] |
| miR-29 | DNMT3B | Burkitt | Down | [142] |
| miR-29b | DNMT3B | Lymphoma, pancreatic, head and neck cell line cancer |
Down | [143,155] |