Figure 1.

Molecular pathways involved in the link between psoriasis and its comorbidities. Psoriasis per se is considered an independent risk factor for atherosclerosis. Moreover, psoriasis is also associated with a high prevalence of traditional modifiable CV risk factors, such as hypertension, diabetes, hyperlipidemia, obesity, and nonalcoholic fatty liver disease (NAFLD) [27,28,29]. Aberrantly activated molecular pathways involved in the link between psoriasis and its comorbidities are indicated.