Table 1.
Results of trials investigating the effects on peak VO2 of exercise training in HFpEF.
| Peak VO2 mL/kg/min |
ET | Ctr | |||
|---|---|---|---|---|---|
| Baseline | Final | baseline | Final | p § | |
| Kitzman 2010 [78] | 13.8 ± 2.5 | 16.1 ± 2.6 * | 12.8 ± 2.6 | 12.5 ± 3.4 | <0.001 |
| Edelmann 2011 [70] | 16.1 ± 4.9 | 18.7 ± 5.4 * | 16.7 ± 4.7 | 16.0 ± 6.0 | <0.001 |
| Smart 2012 [74] | 12.2 ± 3.6 | 15 ± 4.9 * | 14.1 ± 4.1 | 14.8 ± 4.6 | 0.06 |
| Kitzman 2013 [66] | 14.2 ± 2.8 | 15.8 ± 3.3 | 14.0 ± 3.2 | 13.8 ± 3.1 | 0.0001 |
| Maldonado-Martin 2017 [69] | 13.5 ± 2.3 | 16.0 ± 2.6 * | 12.7 ± 3.2 | 12.6 ± 3.4 | 0.01 |
| Brubaker 2020 [71] | 13.7 ± 2.8 | 15.2±6.3 * | 13.3 ± 3.0 | 13.0–14.0 | 0.001 |
| HIIT | MCT | ||||
| Baseline | final | baseline | Final | p § | |
| Angadi 2015 [75] | 19.2 ± 5.2 | 21.0 ± 5.2 * | 16.9 ± 3.0 | 16.8 ± 4.0 | d: 0.94 vs. −1.63 |
| Donelli da Silveira 2020 [76] | 16.1 ± 3.3 | 19.6 ± 3.5 * | 17.6 ± 3.5 | 19.5 ± 3.7 * | <0.001 |
| Mueller 2021 [77] | 18.9 ± 5.4 | 20.2 ± 6.0 | 18.2 ± 5.1 | 19.8 ± 2.5 | 0.002 |
ET: exercise training; Ctr: control group; HIIT: high-intensity interval training; MCT: moderate continuous training. * p < 0.05 pre-intervention vs. post-intervention in the same group; § p: post-intervention between the groups.