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. 2022 Jul 29;12(8):1150. doi: 10.3390/life12081150

Figure 6.

Figure 6

Effect of TA pretreatment on Cd-stimulated decreased renal Bcl-2 expression. Photomicrographs of (A) control and (B) TA-administrated mice showing marked immunostaining of Bcl-2 antibody inside the renal tubular epithelium (arrowhead) (G and T letters indicate renal glomeruli and tubules, respectively); (C) Cd-intoxicated mice demonstrated marked decrease the immunostaining of Bcl-2 antibody inside the renal tubular epithelium (arrowhead) (G and T letters indicate renal glomeruli and tubules, respectively); (D) Cd-intoxicated mice pre-treated with 25 mg TA demonstrated a marked increase in immunostaining of Bcl-2 inside the renal tissues (arrowhead) (G and T letters indicate renal glomeruli and tubules, respectively); (E) Cd-intoxicated mice pre-treated with 50 mg TA demonstrated a marked increase in Bcl-2 immunostaining inside the renal tissues (arrowhead) (G and T letters indicate renal glomeruli and tubules, respectively) (IHC, X 400, bar = 20 µm); (F) Image assessment of Bcl-2 immunostaining in the renal tissue demonstrated a remarkable decrease in Cd-intoxicated mice and a remarkable increase in mice pre-treated with TA. Results are mean ± SEM, (n = 6). a p < 0.05 vs. control, while b p < 0.05 vs. Cd.