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. 2022 Aug 16;11(16):4781. doi: 10.3390/jcm11164781

Table 2.

Characteristics of study participants and comparison between diagnostic and non-diagnostic Holter.

Characteristic Study Cohort
n = 478 (%)
Diagnostic Holter
n = 25 (%)
Non-Diagnostic
n = 453 (%)
p Value
Age, mean ± SD, y 75 ± 14 82 ± 6.2 74 ± 14.5 <0.001
Female gender 217 (45) 9 (36) 16 (64) 0.332
Hypertension 295 (62) 19 (76) 276 (61) 0.131
Diabetes mellitus 140 (29) 11 (44) 129 (28.5) 0.097
Hyperlipidemia 263 (55) 17 (68) 246 (54.5) 0.188
TIA/CVA 82 (17) 8 (32) 74 (16) 0.043
Heart Failure * 0.004
HFrEF 16 (3.3) 1 (4) 15 (3.3)
HFpEF 35 (7.3) 6 (24) 29 (6.4)
Ischemic heart disease 119 (25) 6 (24) 113 (25) 0.910
Structural heart disease † 83 (17) 8 (32) 75 (17) 0.047
Atrial fibrillation 88 (18) 10 (40) 78 (17) 0.004
Beta blocker use 193 (40) 17 (68) 176 (39) 0.004
ND-CCB use 4 (0.8) 0 4 (0.9) 0.637
Antiarrhythmic drugs 18 (3.8) 0 18 (4) 0.310
COPD 40 (8.4) 5 (20) 35 (8) 0.031

Abbreviations: TIA, transient ischemic attack; CVA, cerebrovascular accident; HF, heart failure; rEF, reduced ejection fraction; pEF, preserved ejection fraction; ND-CCB, non-dihydropyridine calcium channel blockers; COPD, chronic obstructive pulmonary disease. *: Reduced ejection fraction includes left ventricular ejection fraction of 40% or less. †: Echocardiographic evidence of either hypertensive/ischemic/valvular heart disease or cardiomyopathy.