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. 2022 Aug 16;11(16):4781. doi: 10.3390/jcm11164781

Table 3.

Clinical variables and comparison between diagnostic and non-diagnostic Holter.

Study Cohort
n = 478 (%)
Diagnostic Holter
n = 25 (%)
Non-Diagnostic
n = 453 (%)
p Value
Time from event to Holter, mean ± SD, d 3.22 ± 3.23 2.04 ± 2.05 3.28 ± 3.35 <0.001
Time from admission to Holter, mean ± SD, d 2.63 ± 2.63 1.24 ± 0.92 2.71 ± 2.67 <0.001
Recurrent syncope * 82 (17) 6 (24) 76 (17) 0.351
Prior syncope admission 72 (15) 2 (8) 70 (15.5) 0.309
Pre-syncopal symptoms † 226 (47) 9 (36) 217 (48) 0.242
Chest pain 22 (4.6) 0 22 (5) 0.259
Palpitations 26 (5.4) 0 26 (6) 0.218
Event during effort 23 (4.8) 1 (4) 22 (5) 0.846
Event at rest 150 (31) 10 (40) 140 (40) 0.340
Oxygen saturation ≤ 93% § 39 (8.1) 1 38 (8) 0.435
Fever > 38 °C 13 (3.0) 0 13 (3) 0.390
Hemoglobin (g/dL) ¶ 13.0 ± 1.8 12.8 ± 1.5 13.0 ± 1.8 0.584
Cardiac exam findings # 114 (24) 9 (36) 105 (23) 0.143
Abnormal ECG 245 (51) 18 (72) 227 (50) 0.033
Traumatic syncope 46 (9.6) 4 (16) 42 (9) 0.267
Hospital stay duration, mean ± SD, d 7.4 ± 6.4 9.6 ± 9.9 7.3 ± 6.1 0.260
In hospital death 2 (0.4) 0 2 (0.4) 0.739

* More than one syncopal event during the seven days before admission. †: Symptoms before syncopal event including dizziness, headache, nausea, and blurred vision. §: Oxygen saturation was measured at rest in ambient air. ¶: First result upon admission, presented as mean and standard deviation. #: Description of a murmur or an irregular rhythm.