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. 2022 Aug 18;20(8):527. doi: 10.3390/md20080527

Table 2.

List of marine-bioinspired metallic nanoparticles for treating non-infectious diseases.

Name of Marine-Derived Compound/Product Organisms/Sources Name of NPs Size Range of MNPs Shape/Morphology Types of Non-Infectious Disease Treatment Effects/Activities References
Extracts
  • Ulva rigida

  • Cystoseira myrica

  • Gracilaria foliifera

AgNPs 12 nm Spherical Anticancer Human breast adenocarcinoma cell line [78]
Extracts
  • Streptomyces sp.

  • Rhodococcus rhodochrous

AgNPs 5.52, 35 nm Spherical
  • Anticancer

  • Anti-leishmanial

  • HepG2 cell line

  • Leishmania tropica

[85]
Extracts Acanthophora spicifera AuNPs <20 nm Spherical Anticancer Human colon adenocarcinoma (HT-29) cells [86]
Extracts Sargassum wighitii MgONPs 68.06 nm Flower Anticancer A549 [88]
Extracts Rhodotorula mucilaginosa Cu2ONPs 51.6–111.4 nm Spherical Anticancer
  • SW620

  • SKOV-3

  • MCF-7

  • HT-29

  • HepG2

  • A549

[117]
Extracts Pterocladia capillacea CuONPs 62 nm Spherical Anticancer Breast cancer, ovarian cancer, and hepatocellular carcinoma cell lines [121]
Extracts Laminaria digitata ZnONPs 100–350 nm Spindle Anticancer Fibroblasts cells and human colon cancer cells [122]
Extracts Hamigera pallidass AgNPs 5.85 ± 0.84, 3.69–16.11 nm Spherical
  • Anticancer

  • Antioxidant

  • Human breast cancer

  • DPPH (2, 2-diphenyl1-picrylhydrazyl)

[123]
Extracts
  • Galaxaura elongate

  • Turbinaria ornata

  • Enteromorpha flexuosa

AgNPs 30–90, 20–60, 30–90 nm Spherical
  • Anticancer

  • Antioxidant

  • Antidiabetic

  • Antiinflammatory

  • HepG2

  • DPPH, ABTS scavenger

  • α-Amylase inhibition

  • Proteinase inhibition and albumin denaturation inhibition

[113]
Extracts U. lactuca AgNPs 8–14 nm Spherical Anticancer Human colon cancer [124]
Extracts Alternaria chlamydospora AuNPs - Spherical
  • Anticancer

  • Antioxidant

  • A549 cell lines

  • DPPH

[125]
Extracts
  • Chondrus crispus

  • Gelidium corneum

  • Porphyra linearis

AuNPs 16.9 ± 2.5, 15.0 ± 3.0, 44.2 ± 6.1 nm Spherical
  • Antitumoral

  • Antioxidant

  • Monocytic cell line

  • Human promyelocytic cells

[126]
Extracts C. crinita ZnONPs 23–200 nm Rectangular Antioxidant DPPH [96]
Extracts Synechocystis sp. AgNPs 10–35 nm Spherical Wound-healing Diabetic wounded animals [97]
Carrageenan &Carrageenan oligosaccharide Marine red algae AuNPs 141 ± 6 nm Spherical Anticancer HCT-116 and HepG2 cells [127]
Extracts Paracoccus haeundaensis AuNPs 20.93 ± 3.46 nm Spherical
  • Anticancer

  • Antioxidant

  • A549

  • AGS cancer cells

  • DPPH

[128]
Extracts Caulerpa taxifolia AgNPs - - Anticancer A549 lung cancer cells [119]
Extracts Nemopilema nomurai AuNPs 35.2 ± 8.7 nm Spherical Anticancer HeLa cancer cells [47]
Extracts Oscillatoria limnetica AgNPs 3.30–17.97 nm Quasi-spherical Anticancer
  • Human colon cancer cell line

  • Human breast cell line

[98]
Extracts Red algae Co3O4NPs 29.8 ± 8.6 nm Spherical Anticancer HepG2 cancer cells [99]
Extracts Vibrio alginolyticus AuNPs 50–100 nm Monodispersed, irregular shape Anticancer HCA-7 cells [120]