AGEs |
Advanced glycation end-products |
ADA |
American Diabetes Association |
Ang-II |
Angiotensin –II |
ACE-i |
Angiotensin-converting enzyme inhibitors |
ARBs |
Angiotensin Receptor Blockers |
ADMA |
Asymmetric dimethylarginine |
BNP |
Brain-Natriuretic-Peptide |
CV |
Cardiovascular |
CKD |
Chronic Kidney Disease |
DM |
Diabetes Mellitus |
DN |
Diabetic nephropathy |
DKD |
Diabetic kidney disease |
ESKD |
End-stage-kidney-disease |
ERA |
Endothelin-1 receptor antagonists |
ETAr |
Endothelin-1 binding to ET receptors type A |
eGFR |
Estimated glomerular filtration rate |
ECM |
Extracellular matrix |
KDIGO |
Global Outcomes Work Group |
GLP1-RA |
Glucagon-like peptide-1 receptor agonists |
GDF-15 |
Growth differentiation factor-15 |
hs-cTnT and hs-cTnI |
High-sensitivity cardiac troponins |
IGF-1 |
Insulin-like growth factor 1 |
JAK-STAT |
Janus kinase/signal transducers and activators of transcription |
KIM-1 |
Kidney Injury Molecule -1 |
mTORC1 |
Mammalian target of rapamycin complex 1 |
MACE |
Major cardiovascular events |
MMP-10 |
Matrix metalloproteinases—10 |
MRA |
Mineralocorticoid receptor antagonist |
NGAL |
Neutrophil Gelatinase-Associated Lipocalin |
NO |
Nitric oxide |
NP-DN |
Non-proteinuric diabetic nephropathy |
NF-κB |
Nuclear factor-κB |
PKC |
Protein kinase C |
uPAR |
Protein urokinase receptor |
ROS |
Reactive oxygen species |
RAASi |
Renin-angiotensin-system inhibitors |
RBP-4 |
Retinol-binding protein-4 |
SGLT2is |
Sodium-glucose co-transporter inhibitors |
suPAR |
Soluble urokinase-type plasminogen activator receptor |
SDMA |
Symmetric Dimethylarginine |
T1DM |
Type 1 diabetes mellitus |
T2DM |
Type 2 diabetes mellitus |
TGF-β1 |
Transforming growth factor—β1 |
TNFR-1 and TNFR-2 |
Tumor Necrosis Factors receptors |
ULK1 |
Unc-51-like kinase 1 |
VEGF |
Vascular endothelial growth factor |