DM |
Diabetes Mellitus |
T2DM |
Type 2 Diabetes Mellitus |
DPP-IV |
Dipeptidyl peptidase 4 |
GLP-1 |
Glucagon-like peptide-1 |
GIP |
Glucose-dependent insulinotropic polypeptide |
IL |
Interleukin |
TNF |
Tumor necrosis factor |
SGLT2 |
Sodium-glucose cotransporter-2 |
PPAR |
Peroxisome proliferator-activated receptors |
VEGF |
Vascular endothelial growth factor |
TG |
Triglycerides |
HDL |
High-density lipoprotein |
LDL |
Low-density lipoprotein |
VLDL |
Very low-density lipoprotein |
HMG-CoA |
3-hydroxy-3-methylglutaryl coenzyme A |
HFD |
High fat fed |
CTGF |
Connective tissue growth factor |
TGF-β1 |
Transforming growth factor-β1 |
CYP2E1 |
Cytochrome P450 2E1 |
BMI |
Body mass index |
NAFLD |
Non-alcoholic fatty liver disease |
NA |
Nicotinamide |
ALT |
Alanine transaminase |
AST |
Aspartate transaminase |
STZ |
Streptozotocin |
AGE |
Advanced Glycation End Products |
IRS-1 |
Insulin receptor substrate 1 |
AMPK |
AMP-activated protein kinase |
PEPCK |
Phosphoenolpyruvate carboxykinase |
G6Pase |
Glucose 6 Phosphate |
Akt |
Protein kinase B |
AMP |
Adenosine monophosphate |
ATP |
Adenosine triphosphate |
ROS |
Reactive oxygen species |
MMP-9 |
Matrix metalloproteinase 9 |
MCP-1 |
Monocyte chemoattractant protein-1 |
JNK |
c-Jun N-terminal kinase |
NF-κB |
Nuclear transcription factor kappa-B |
PKC |
Protein kinase C |
Syk |
Spleen tyrosine kinase |
MAPK |
p38 mitogen-activated protein kinase |
COX-2 |
Cyclooxygenase-2 |
GPX4 |
Glutathione peroxidase 4 |
NPC1L1 |
Niemann-Pick C1-Like 1 |
RAAS |
Renin-angiotensin-aldosterone system |