Table 3.

Univariate and multivariate analyses for PTMC patients with unilateral disease.

	Univariate Analysis		Multivariate Analysis			Univariate Analysis		Multivariate Analysis
	Hazard Ratio (95% CI)	p Value	Hazard Ratio (95% CI)	p Value		Hazard Ratio (95% CI)	p Value	Hazard Ratio (95% CI)	p Value
Factors selected					Factors selected
Age		0.000		0.000	Age		0.261
≥55 vs. <55	0.426 (0.273–0.666)		0.360 (0.213–0.609)		≥55 vs. <55	0.426 (0.096–1.886)
BMI		0.436			BMI		0.596
>23 vs. ≤23	0.876 (0.629–1.222)				>23 vs. ≥23	0.812 (0.375–1.758)
Gender		0.000		0.000	Gender		0.749
Male vs. Female	2.336 (1.639–3.329)		2.505 (1.643–3.818)		Male vs. Female	1.134 (0.525–2.446)
TCI		0.000		0.000	TCI		0.205
Yes vs. No	6.228 (4.171–9.299)		5.894 (3.736–9.299)		Yes vs. No	1.656 (0.759–3.616)
Maximum tumor diameter		0.000		0.000	Maximum tumor diameter		0.228
>0.5 cm vs. ≤0.5 cm	2.788 (1.978–3.929)		2.181 (1.456–3.269)		>0.5cm vs. ≤0.5cm	1.694 (0.719–3.993)
Tumor location		0.752			Tumor location		0.683
Upper vs. Middle/Lower	0.939 (0.637–1.384)				Upper vs. Middle/Lower	1.199 (0.501–2.870)
Multifocality		0.000		0.000	Multifocality		0.001		0.010
Yes vs. No	4.692 (3.103–7.095)		4.514 (2.831–7.196)		Yes vs. No	4.305 (1.872–9.899)		4.439 (1.423–13.847)
PTMC with ipsilateral nodular goiter		0.936			PTMC with ipsilateral nodular goiter		0.000		0.003
Yes vs. No	1.015 (0.701–1.470)				Yes vs. No	4.196 (1.901–9.258)		6.311 (1.883–21.159)
PTMC with Hashimoto thyroiditis		0.310			PTMC with Hashimoto thyroiditis		0.964
Yes vs. No	0.798 (0.516–1.234)				Yes vs. No	1.024 (0.366–2.869)
					Maximum diameter of positive CLN		0.000		0.000
					>0.5cm vs. ≤0.5cm	71.697 (16.284–315.670)		107.399 (20.011–576.400)
					Number of positive CLN		0.001		0.826
					≥3 vs. <3	2.282 (1.429–3.644)		0.924 (0.458–1.866)

CI, confidence interval; PTMC, papillary thyroid microcarcinoma; TCI, thyroid capsular invasion; BMI, body mass index; CLN, central lymph node.