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Scatter plot of the MR estimates for the association of serum TIMP3 levels with risk of CAD and MI based on CARDIoGRAMplusC4D (A,B) and FinnGen (C,D). TIMP3, tissue inhibitors of matrix metalloproteinase 3; CAD, coronary artery disease; MI, myocardial infarction; CARDIoGRAMplusC4D, Coronary Artery Disease Genome−Wide Replication and Meta−Analysis plus the Coronary Artery Disease Genetics; MR−PRESSO, MR Pleiotropy Residual Sum and Outlier. Dots refer to SNPs.
