Naked mRNA |
Intramuscular |
Tumors |
Humoral |
Mice |
[60] |
Intramuscular |
Influenza, RSV, Encephalitis |
Humoral |
Mice |
[61] |
Intradermal |
Influenza |
Humoral/Cellular |
Mice, Human |
[56] |
Intranodal |
Influenza |
Humoral |
Mice |
[43] |
Intranasal |
Tuberculosis |
Humoral |
Mice |
[65] |
Dendrimer |
Intramuscular |
Ebola, Influenza and Toxoplasma |
Humoral/Cellular |
Mice |
[91] |
Intramuscular |
Zika |
Humoral/Cellular |
Mice |
[121] |
Protamine |
Intradermal, Intramuscular |
Rabies virus |
Humoral |
Mice, Pigs, and human |
[82] |
Intradermal |
Influenza |
Humoral/Cellular |
Mice, Ferrets, and pigs |
[122] |
Intradermal |
Prostate cancer |
Cellular |
Human |
[123] |
Polymer |
Intramuscular |
Influenza |
Humoral |
Mice |
[124] |
Intranasal |
HIV-gp120 |
Humoral |
Mice |
|
Intramuscular |
HIV-Gag and Pol |
Humoral/Cellular |
Mice |
[93] |
Subcutaneous |
Zika |
Humoral/Cellular |
Mice, Rabbit |
[90] |
Lipid nanoparticle |
Intradermal |
Zika |
Humoral |
Mice, Primates |
[12] |
Intramuscular |
Ebola |
Humoral |
Guinea pigs |
[125] |
Intradermal |
HIV-Env |
Humoral/Cellular |
Mice |
[126] |
Intravenous |
HIV-IgG |
Humoral |
Mice |
[127] |
Intramuscular |
SARS-CoV2 |
Humoral |
Human |
[128,129] |
Cationic nanoemulsion |
Sub cutaneous |
HIV—Gag |
Humoral |
Mice |
[130] |
Intramuscular |
RSV, CMV, HIV |
Humoral |
Mice, Rabbit, Macaques |
[117] |
Intramuscular |
Encephalitis |
Humoral |
Mice |
[120] |
Virus-like replicon particle |
Intradermal |
Dengue |
Humoral |
Macaques |
[131] |
Intravenous, Intramuscular |
Influenza |
Humoral/Cellular |
Mice, Swine |
[132] |
Intramuscular |
HIV |
Humoral/Cellular |
Mice |
[133] |
Subcutaneous, Intramuscular |
Ebola |
Cellular |
Primates |
[134] |
Intramuscular |
SARS-CoV |
Humoral |
Mice |
[135] |
Intranasal |
MERS-CoV |
Humoral |
Mice |
[136] |
Intradermal |
RSV |
Humoral |
Primates |
[137] |
Subcutaneous, intramuscular |
CMV |
Humoral |
Human |
[138] |