Table 5.
Risk factors analysis for cranial nerve palsy after GKRS.
| Univariate | |||
|---|---|---|---|
| HR | 95%CI | p Value | |
| age | 1.20 | (1.03–1.40) | 0.022 * |
| Sex | |||
| Male | ref. | ||
| Female | 0.56 | (0.05–6.42) | 0.643 |
| WBC (Pre GKRS)/μL | 1.00 | (1.00–1.00) | 0.061 |
| Tumor volume (cc) | 2.09 | (1.04–4.19) | 0.038 * |
| Number of isocenter | 1.17 | (0.90–1.51) | 0.235 |
| Maximum dose (Gy) | 1.07 | (0.81–1.42) | 0.632 |
| Peripheral isodose line (%) | 0.94 | (0.77–1.16) | 0.561 |
| Margin dose (Gy) | 0.79 | (0.23–2.73) | 0.704 |
| Rt optic nerve dosage (Gy) | 1.53 | (0.84–2.79) | 0.167 |
| Lt optic nerve dosage (Gy) | 1.18 | (0.65–2.17) | 0.585 |
| Chiasma dosage (Gy) | 1.40 | (0.56–3.48) | 0.470 |
| Pituitary stalk dosage (Gy) | 1.90 | (0.62–5.84) | 0.262 |
| Brain stem dosage (Gy) | 1.18 | (0.82–1.71) | 0.378 |
| Rt lateral cavernous sinus wall dosage (Gy) | 1.43 | (0.99–2.07) | 0.060 |
| Lt lateral cavernous sinus wall dosage (Gy) | 1.02 | (0.82–1.27) | 0.888 |
| IOP at GK (mmHg) | 1.30 | (0.87–1.94) | 0.205 |
| Schirmer’s test at GKRS (mm) | 0.53 | (0.15–1.88) | 0.328 |
| Percentage of Rt ICA > 20 Gy (%) | 1.05 | (0.98–1.12) | 0.140 |
| Percentage of Lt ICA > 20 Gy (%) | 1.04 | (0.96–1.13) | 0.339 |
| Percentage of Lt ICA (>20 Gy vs. ≤20 Gy) | 0.70 | (0.10–5.16) | 0.730 |
Cox regression. * p < 0.05, Rt = right; Lt = left.