Table 3.

Regression analysis of imaging markers of diastolic dysfunction and myocardial fibrosis by NT-proBNP (at intervals of 50 ng/L).

Variables (Unit)	b	95 % CI	p-Value	N	R2
SCD Risk Score (%)	0.006	−0.001–0.012	0.095	329	0.11
LA diameter (mm)	0.026	0.006–0.046	0.010	355	0.18
Resting LVOT flow gradient (ln *)	1.005	1.003–1.007	<0.001	355	0.13
Provoked LVOT flow gradient (ln *)	1.003	0.999–1.006	0.101	278	0.11
E/E′ mean	0.058	0.045–0.072	<0.001	347	0.28
E/E′ septal	0.080	0.060–0.100	<0.001	349	0.25
E/E′ lateral	0.049	0.036–0.062	<0.001	349	0.22
IVRT septal	0.165	0.078–0.252	<0.001	343	0.09
IVRT lateral	0.218	0.146–0.290	<0.001	345	0.12
SW thickness (mm)	0.035	0.024–0.047	<0.001	356	0.11
LGE size (g)	0.123	0.068–0.179	<0.001	190	0.11

b = unstandardized regression coefficient, CI = confidence interval, R² = adjusted coefficient of determination. * For logarithmized parameters the exponentiated regression estimates and confidence intervals are presented. Abbreviations: E = peak early transmitral filling velocity, E′ = early mitral annulus velocity, IVRT = isovolumetric relaxation time, LA = left atrial, LGE = late gadolinium enhancement, ln = logarithmized, LVOT = left ventricular outflow tract, SCD = sudden cardiac death, SW = septal wall.