Table 2.
Comparison of the entire population between the time T0 and T1.
| TO Time | T1 Time | p Value | |
|---|---|---|---|
| FeNO 50, ppb m ± sd | 73.40 ± 76.41 | 68.86 ± 69.74 | 0.595 |
| EOS, cells/μL median (IQ 25–75) | 680.00 (500.00–959.00) | 130.00 (97.50–447.50) | 0.004 |
| IGE tot, KU/L median (IQ 25–75) | 234.00 (119.00–534.50) | 400.00 (215.00–700.00) | 0.756 |
| FEV1, m ± sd % predicted | 73.37 ± 21.72 | 85.67 ± 16.07 | 0.000 |
| FVC, m ± sd % predicted | 94.66 ± 17.91 | 96.51 ± 16.13 | 0.000 |
| RV, m ± sd % predicted | 110.28 ± 28.08 | 112.00 ± 23.99 | 0.113 |
| ACT, score m ± sd | 14.41 ± 5.03 | 20.70 ± 4.31 | 0.219 |
| ACQ, score m ± sd | 1.95 ± 0.96 | 0.93 ± 0.69 | 0.431 |
| Need of inhaled reliever medication, % | 63.8 | 21.2 | 0.007 |
| OCS, yes % | 66.6 | 45.7 | 0.353 |
| Average dose of OCS, mg m ± sd | 13.59 ± 12.37 | 4.05 ± 7.04 | 0.550 |
| FACED, score m ± sd | 2.18 ± 1.16 | 1.42 ± 1.27 | 0.172 |
| % Positive sputum | 16.7 | 5.5 | 0.125 |
| Mucolytic therapy, yes % | 35 | 35 | 1.000 |
| Adherence to therapy % | 89 | 95 | 0.200 |
| WBCs, cells/μL median (IQ 25–75) | 7000.00 (6500.00–9725.00) | 7100.00 (6590.00–10,420.00) | 0.998 |
FeNO: exhaled nitric oxide; EOS: blood eosinophilia; FEV1: forced expiratory volume in the 1st second; FVC: forced vital capacity; IgE: immunoglobulin E; VR: residual volume; ACT: asthma control test; ACQ: asthma control questionnaire; OCS: oral corticosteroid; WBCs: white blood cells; LTRA: leukotriene receptor antagonist.