Table 4.
Univariate analysis comparing odds ratios of baseline parameters to mean differences of meibomian gland grade in patients with moderate to severe meibomian gland dysfunction.
| Baseline Parameter | Odds Ratio | 95% Confidence Interval | p Value 1 | ||
|---|---|---|---|---|---|
| Lowest | Highest | ||||
| Sex | Female | 1 | |||
| Male | 0.586 | 0.122 | 2.800 | 0.503 | |
| Age (year) | 0.919 | 0.832 | 1.015 | 0.008 | |
| TBUT (s) | 0.660 | 0.296 | 1.471 | 0.310 | |
| SICCA staining score | 1.298 | 0.905 | 1.862 | 0.015 | |
| Oxford staining score | 1.386 | 0.663 | 2.895 | 0.385 | |
| Meibum color | Upper eyelid (0–3) |
3.429 | 0.274 | 42.956 | 0.339 |
| Lower eyelid (0–3) |
7.000 | 0.392 | 125.040 | 0.186 | |
| Meibum consistency | Upper eyelid (0–3) |
15.782 | 1.916 | 130.021 | 0.010 |
| Lower eyelid (0–3) |
9.611 | 2.033 | 4.443 | 0.004 | |
| Lid margin telangiectasia | Upper eyelid (0–3) |
1.543 | 0.325 | 7.333 | 0.586 |
| Lower eyelid (0–3) |
0.571 | 0.063 | 5.193 | 0.619 | |
| MMP-9 level | 2.856 | 1.130 | 7.219 | 0.027 | |
| Schirmer test | 1.242 | 0.917 | 1.682 | 0.162 | |
TBUT, tear film break-up time; SICCA, Sjögren’s International Clinical Collaborative Alliance; MMP-9, matrix metalloproteinase-9. 1 Statistical analysis was performed with univariate analysis using a logistic regression model.