Table 3.

Variables associated with amputation.

	OR (CI)	P value	Adjusted OR (CI)	P value
Age	1.03 (1.00–1.06)	0.031	1.03 (0.99–1.07)	.196
Male gender	1.42 (0.45–4.50)	0.549
Non-White race	0.62 (0.25–1.53)	0.297
Intoxication on admission	0.69 (0.29–1.63)	0.399
History of drug and/or alcohol use	4.91 (1.40–17.21)	0.013	1.40 (1.07–10.68)	.038
Substance use disorder	0.74 (0.30–1.82)	0.509	6.03 (1.16–31.46)	.033
Other psychiatric disorder	3.33 (1.26–8.83)	0.016	1.89 (0.60–5.93)	.275
Charlson Comorbidity Index	1.08 (0.84–1.39)	0.545
History of frostbite injury	1.34 (0.30–4.34)	0.853
Thrombolytics	2.30 (0.87–6.12)	0.095	3.38 (1.07–10.68)	.038
Medical discharge disposition
Home or stable housing	1		1
Homeless shelter	0.74 (0.08–6.50)	0.783	0.39 (0.04–3.75)	.416
Inpatient psychiatry	2.87 (0.64–12.96)	0.170	1.80 (0.34–9.57)	.492
Other healthcare facility	6.24 (2.26–17.22)	<0.001	3.94 (1.07–14.45)	.039
Against medical advice (to various locations)	1.20 (0.13–11.01)	0.874	0.70 (0.07–6.82)	.755

Univariable and multivariable logistic regression.

CI = confidence interval, OR = odds ratio.