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Slice thickness effects on SD propagation. K+ wave speed during SD in perfused and hypoxic slices of various thicknesses. SD could not be initiated in very thin (100 μm) slices when perfused but could in hypoxic slices. For perfused slices, K+ wave speed increased with slice thickness between 200 and 400 μm then saturated for slices of greater thickness. A similar pattern was observed in the hypoxic slices with consistently faster K+ wave speeds compared with in perfused slices.
