Table 2.
Pairwise comparisons of treatments.
| Amitriptyline | -0.07 (-0.79; 0.64) | . | . | . | . | . | . | . | . | -0.24 (-0.72; 0.24) | . | . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| -0.08 (-0.75; 0.58) | Carbamazepine | . | . | . | . | . | . | . | . | -0.15 (-0.87; 0.57) | . | . |
| 0.68 (-0.33; 1.68) | 0.76 (-0.35; 1.86) | Etanercept | . | . | . | . | . | . | . | -0.92 (-1.80; -0.03) | . | . |
| 0.08 (-0.79; 0.95) | 0.17 (-0.82; 1.15) | -0.59 (-1.74; 0.55) | Ketamin | . | . | . | . | . | . | -0.32 (-1.05; 0.41) | . | . |
| 1.15 (0.21; 2.10) | 1.24 (0.18; 2.29) | 0.48 (-0.72; 1.68) | 1.07 (-0.02; 2.16) | Lamotrigine | . | . | . | . | . | -1.39 (-2.21; -0.58) | . | . |
| 1.88 (0.89; 2.86) | 1.96 (0.87; 3.04) | 1.20 (-0.03; 2.43) | 1.79 (0.67; 2.92) | 0.72 (-0.46; 1.90) | Levetiracetam | . | . | . | . | -2.11 (-2.97; -1.26) | . | . |
| 0.41 (-0.45; 1.27) | 0.49 (-0.48; 1.46) | -0.27 (-1.40; 0.86) | 0.33 (-0.69; 1.34) | -0.75 (-1.83; 0.34) | -1.47 (-2.58; -0.35) | Lidocaine | . | . | . | -0.65 (-1.36; 0.06) | . | . |
| 0.41 (-0.47; 1.28) | 0.49 (-0.50; 1.48) | -0.27 (-1.42; 0.88) | 0.32 (-0.71; 1.36) | -0.75 (-1.84; 0.35) | -1.47 (-2.60; -0.34) | -0.00 (-1.02; 1.02) | Morphine | . | . | -0.65 (-1.38; 0.09) | . | . |
| -0.22 (-1.00; 0.57) | -0.13 (-1.04; 0.77) | -0.89 (-1.97; 0.19) | -0.30 (-1.26; 0.66) | -1.37 (-2.39; -0.35) | -2.09 (-3.15; -1.03) | -0.62 (-1.57; 0.32) | -0.62 (-1.58; 0.34) | Naloxone | . | -0.02 (-0.64; 0.60) | . | . |
| 2.19 (0.98; 3.40) | 2.27 (0.97; 3.57) | 1.51 (0.09; 2.93) | 2.11 (0.78; 3.43) | 1.03 (-0.34; 2.41) | 0.31 (-1.09; 1.72) | 1.78 (0.46; 3.10) | 1.78 (0.45; 3.12) | 2.40 (1.13; 3.68) | Pamidronate | . | -0.05 (-0.91; 0.81) | . |
| -0.24 (-0.72; 0.24) | -0.16 (-0.82; 0.51) | -0.92 (-1.80; -0.03) | -0.32 (-1.05; 0.41) | -1.39 (-2.21; -0.58) | -2.11 (-2.97; -1.26) | -0.65 (-1.36; 0.06) | -0.65 (-1.38; 0.09) | -0.02 (-0.64; 0.60) | -2.43 (-3.54; -1.31) | Placebo | 2.38 (1.67; 3.09) | 0.46 (0.22; 0.71) |
| 2.14 (1.28; 3.00) | 2.22 (1.25; 3.19) | 1.46 (0.33; 2.60) | 2.06 (1.04; 3.07) | 0.99 (-0.10; 2.07) | 0.26 (-0.85; 1.38) | 1.73 (0.73; 2.74) | 1.73 (0.71; 2.75) | 2.36 (1.41; 3.30) | -0.05 (-0.91; 0.81) | 2.38 (1.67; 3.09) | Prednisone | . |
| 0.23 (-0.31; 0.76) | 0.31 (-0.40; 1.02) | -0.45 (-1.37; 0.46) | 0.14 (-0.63; 0.91) | -0.93 (-1.78; -0.08) | -1.65 (-2.54; -0.76) | -0.18 (-0.94; 0.57) | -0.18 (-0.96; 0.59) | 0.44 (-0.23; 1.11) | -1.96 (-3.10; -0.82) | 0.46 (0.22; 0.71) | -1.91 (-2.67; -1.16) | Pregabalin |
Footnotes: The comparisons between any two treatments should be read from left to right, and the comparison estimate (expressed as standard mean difference [SMD] and its related 95%CI) is in the cell between the column-defining treatment and the row-defining treatment. The top half of the table presents SMDs from direct comparison evidence, while the bottom half of the table presents SMDs from network meta-analysis. In top half, SMDs >0 favor row-defining treatments vs. column-defining treatments. In the bottom half, SMDs <0 favor column-defining treatments. Empty cells indicate no direct comparison between two treatments.