Figure 5.

Effects of COG1410 on hippocampal apoptosis at 72 h after cerebral I/R. (a) Representative images of TUNEL staining in the hippocampal CA1 area (×400); nuclei were labeled with blue fluorescence (DAPI), and TUNEL-positive cells were labeled with red fluorescence, scale bars = 20 μm. (b) Representative bands of Western blot data. (c) Quantitative analyses of TUNEL-positive cells in the hippocampal area. (d–f) Quantitative analysis of the Western blot bands. Data were represented as mean ± SEM. Western blot, n = 6 per group; TUNEL staining, n = 8 per group. ^∗P < 0.05, ^∗∗P < 0.01 vs. sham group; ^#P < 0.05, ^##P < 0.01 vs. I/R + Vehicle group.