Table 1.
Structural feature comparison for all crystal structure complexes reported in the present study
| Homopurine mismatches | Watson–Crick base pairs | |||||
|---|---|---|---|---|---|---|
| Complex name | A:G | G:A-CPX1 | G:A-CPX2 | C:G | G:C-CPX1 | G:C-CPX2 |
| Central base-pair | A4:G11 | G4:A11 | G4:A11 | C4:G11 | G4:C11 | G4:C11 |
| Central base-pair geometry | anti–anti | syn–anti | ‘syn’ like anti–anti | anti–anti | syn–anti | syn–anti |
| Central base-pair type | Wobble | Wobble | Sugar-edged | Watson–Crick | Hoogsteen | Hoogsteen |
| Central base-pair C1'–C1' distance (Å) | 12.3 | 10.5 | 9.0 | 10.8 | 9.4 | 8.8 |
| ActD and Echi intercalation type | Parallel | Parallel | Slanted | Parallel | Parallel | Slanted |
| DNA conformation | Single strand distortion | Single strand distortion | Sharp bend | Single strand distortion | Four-way junction | Kinked |
| Backbone shape | ‘Chair’ shape | ‘Chair’ shape | ‘Curve’ shape | ‘Chair’ shape | Antiparallel crossover | ‘Zig-zag’ shaped |
| ActD | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Echi | ✓ | ✓ | ✓ | ✓ | ✗ | ✓ |
| PDB ID | 7X6R | 7XDJ | 7X97 | 7X9F | ||