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. 2022 Jul 25;50(15):8867–8881. doi: 10.1093/nar/gkac629

Table 1.

Structural feature comparison for all crystal structure complexes reported in the present study

Homopurine mismatches Watson–Crick base pairs
Complex name A:G G:A-CPX1 G:A-CPX2 C:G G:C-CPX1 G:C-CPX2
Central base-pair A4:G11 G4:A11 G4:A11 C4:G11 G4:C11 G4:C11
Central base-pair geometry anti–anti syn–anti ‘syn’ like anti–anti anti–anti syn–anti syn–anti
Central base-pair type Wobble Wobble Sugar-edged Watson–Crick Hoogsteen Hoogsteen
Central base-pair C1'–C1' distance (Å) 12.3 10.5 9.0 10.8 9.4 8.8
ActD and Echi intercalation type Parallel Parallel Slanted Parallel Parallel Slanted
DNA conformation Single strand distortion Single strand distortion Sharp bend Single strand distortion Four-way junction Kinked
Backbone shape ‘Chair’ shape ‘Chair’ shape ‘Curve’ shape ‘Chair’ shape Antiparallel crossover ‘Zig-zag’ shaped
ActD
Echi
PDB ID 7X6R 7XDJ 7X97 7X9F