Table 1.

Gapmers ASOs used in this study. dN = DNA, +N = LNA, uN = 2′-O-MOE, d5C = 5-methyl-deoxycytosine. All internucleotide linkages were phosphorothioate

Target	Oligo name	Sequence (5′-3′)	Calculated mass	Observed mass
NTC	NTC_1	+A+A+CdAd5CdGdTd5CdTdAdTdA+C+G+C	4984.1	4983.6
	NTC_2	+A+T+TdTdTdAdTdTd5CdGdGdA+G+C+T	4994.0	4994.5
Malat1	Malat1_1	uGuGuGuUuCdAdGdCdTdGdCdCdAdAdTuGuCuUuAuG	7232.1	7232.0
	Malat1_2	+G+G+TdCdAdGdCdTdGdCdCdA+A+T+G	4985.9	4985.5
	Malat1_3	+C+T+AdGdTdTd5CdAd5CdTdGdAdA+T+G+C	5321.3	5320.5
Cd47	Cd47_4	+G+T+Gd5CdTdTdGdGd5CdGdAdGdT+C+T+C	5369.3	5368.5
Cd98	Cd98_6	+A+C+CdGdGd5Cd5Cd5CdGdAdAdTd5C+T+C+G	5334.4	5334.0
Mfap4	Mfap_4	+C+C+AdTdTdGdGdGd5Cd5Cd5CdAdA+T+T+G	5336.3	5337.3
Adam33	Adam33_1	+T+A+AdGd5CdTd5CdAdGdAdGdT+T+C+G	5027.1	5027.6