Table 1.

Summary of cases with and without abnormal mammillary body (MB) signal across sites.

Centre	Number of cases with normal MB signal	Number of cases with abnormal MB signal	Grade of neonatal encephalopathy I/II/III/NA		Pattern of injury normal/watershed/BGT/NT
			Cases with normal MB signal	Cases with abnormal MB signal	Cases with normal MB signal	Cases with abnormal MB signal
Leiden % within the MB group % of all cases in the subgroup	75	61 (44.9%)	36/24/14/1 48%/32%/19%/1% 59%/55%/48%/50%	25/20/15/1 41%/33%/24%/2% 41%/45%/52%/50%	51/6/13/5 68%/8%/17%/7% 58%/66%/59%/29%	37/3/9/12 60%/5%/15%/20% 42%/33%/41%/71%
Genoa % within the MB group % across subgroup	52	31 (37.3%)	11/34/5/2 21%/65%/10%/4% 85%/61%/42%/100%	2/22/7/0 6%/71%/23%/0% 15%/39%/58%/0%	32/10/5/5* 62%/19%/10%/10% 24%/67%/42%/33%	9/5/7/10* 29%/16%/23%/33% 22%/33%/58%/67%
Combined % within MB group % across subgroup	127	92 (41.6%)	47/58/19/3 37%/46%/15%/2% 64%/58%/46%/75%	27/42/22/1 29%/46%/24%/1% 36%/42%/54%/25%	83/16/18/10** 65%/13%/14%/8% 64%/67%/53%/31%	46/8/16/22** 50%/9%/17%/24% 36%/33%/47%/69%

NA: Could not be assessed due to high dose of sedatives. Pattern of injury: no abnormalities (normal), damage into the watershed areas, damage predominantly to the deep grey matter, that is, basal ganglia/thalamus (BGT), and severe brain damage, that is, near-total brain injury (NT).

*P = 0.007 MB abnormalities vs no MB abnormality (Genoa, χ²).

**P = 0.003 normal/watershed vs BGT/NT (Combined, χ²).