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. 2022 Aug 12;13:863034. doi: 10.3389/fimmu.2022.863034

Figure 2.

Figure 2

Dex injection HYPERLINK "D:/LenovoDrivers/%E6%9C%89%E9%81%93/Dict/8.9.3.0/resultui/html/index.html#/javascript:;"aggravated OXA induced colitis. DEX (5 mg/kg) or vehicle was injected for 7 consecutive days and then the mice received 1% OXA enema to induce colitis. (A) The serum corticosterone level of WRS and control group mice was measured by ELISA kit. (B) Weight changes and colon length (C, D) of DEX injection and control mice at day 1 after 1% OXA enema. (E, F) Representative HE staining of colonic sections [×20] and pathological score of inflamed colonic tissue. (G, H) qPCR of Il-6 and Tnf-α mRNA in colonic tissues of control and DEX injection mice at day 1 after 1% OXA enema. (I) Immunoblot of ZO-1 and Occludin of control and DEX injection mice at day 1 after 1% OXA enema. Data are representative of at least two independent experiments. Data are shown as mean ± SEM. **p <0.01; ***p <0.001; ****p <0.0001.