Fig. 5.

Cellular crosstalk of endothelial cells and podocytes in diabetic kidney disease. (HB-EGF, heparin-binding epidermal growth factor-like growth factor; TGF-β, transforming growth factor-β; HGF, hepatocyte growth factor; FAT, fatty acid translocase; LRG-1, leucine-rich α-2-glycoprotein 1; PDGFB, platelet-derived growth factor B; APC, activated protein C; KLF2, Kruppel -like factor 2; eNOS, endothelial nitric oxide synthase; VEGF-A, vascular endothelial growth factor A; VEGF-B, vascular endothelial growth factor B; MCP-1, monocyte chemotactic protein 1; ET-1, endothelin-1; SDF-1, stromal cell-derived factor-1; Ang, angiopoietin; CCL21, C–C chemokine ligand 21; CCN2, cellular communication network factor 2;)