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. 2022 Aug 25;13(8):734. doi: 10.1038/s41419-022-05173-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A The expression of lncRNA HEPFAL in HCC is lower than that in normal tissues (n = 368 in TCGA database). B The expression of SLC7A11 in HCC is higher than that in normal tissues (n = 368 in TCGA database). C Based on the median expression of lncRNA HEPFAL, patients were divided into high-expression and low-expression groups, and the Kaplan–Meier survival curve of 368 HCC patients was drawn. D, E qRT-PCR detects the expression of lncRNA HEPFAL in tumor tissues and matched normal tissues (n = 60 in WMU hospital). F Kaplan–Meier survival curve of overall survival in 60 HCC patients according to the lncRNA HEPFAL expression. Patients were stratified into high and low expression groups by median expression. G, H qRT-PCR detects the expression of lncRNA HEPFAL and SLC7A11. I The expression of SLC7A11 was detected by western blot. J IHC detected SLC7A11 expression in tumor tissues with high and low lncRNA HEPFAL expression. ***P < 0.001.