Fig. 1. Associations between polygenic risk for coronary artery disease and quantitative traits derived from lab values, clinical exam, self-report, and clinical scores in the Women’s Health Initiative.

Positive associations are plotted in the up direction and negative associations are plotted in the down direction. Associations that are significant with FDR q-value ≤ 0.05 are labeled. The horizontal gray dashed lines represent the Bonferroni significant p-value < 9.2 × 10⁻⁵ (0.05/546). Sample size for each test is included in the Quantitative outcomes section of the Supplementary Data.