Fig. 5. Association between polygenic risk for coronary artery disease and causes of death in the Women’s Health Initiative.

Cox analysis was performed to measure the risk of death for each given cause. Non-cases were censored at time of death from any other cause or time of last follow-up. Models were adjusted for smoking status, self-reported diabetes at baseline, systolic blood pressure, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol. Hazard ratios (HR) are per 1 standard deviation increase in the polygenic risk score. Error bars represent 95% confidence intervals.