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. 2022 Aug 25;7:50. doi: 10.1038/s41525-022-00320-1

Fig. 4. Labs as imputed by methylation, genotypes, and an externally-trained polygenic risk score.

Fig. 4

The cross-validated R2 between the true and imputed lab value on 541 unrelated patients of non-Hispanic-Latino white-identifying individuals using a baseline predictor as well as a baseline predictor with methylation, genotypes, and a PRS externally-trained from UKBiobank summary statistics. HDL corresponds to high-density lipoprotein cholesterol and HGBA1C to glycated hemoglobin. Error bars indicate 95% confidence intervals.