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. 2022 Aug 25;7:50. doi: 10.1038/s41525-022-00320-1

Table 1.

Replication statistics within ethnic groupings.

Outcome Metric Accuracy, p-value Hispanic/Latino (n = 118) Accuracy, p-value white, non-Hispanic/Latino (n = 543) Accuracy, p-value all ethnicities (n = 833)
Creatinine R2 0.217, 4.63e−07 0.356, 7.47e−46 0.457, 1.27e−95
Hematocrit R2 0.045, 2.91e−02 0.188, 1.87e−21 0.246, 1.14e−42
Hemoglobin R2 0.096, 1.21e−03 0.204, 2.54e−23 0.283, 3.02e−50
Mean corpuscular hemoglobin R2 0.050, 2.12e−02 0.122, 9.70e−14 0.208, 7.04e−35
Urea nitrogen R2 0.289, 2.97e−09 0.349, 7.61e−44 0.435, 2.50e−87
CMV Agents AUC 0.874, 9.27e−07 0.875, 3.47e−16 0.905, 1.72e−38
Osmotic Diuretics AUC 0.530, 0.841 0.842, 2.27e−12 848, 6.37e−34
Phosphate binder agents AUC 0.608, 0.321 0.819, 7.76e−17 0.876, 1.11e−50
Hematopoietic growth factors AUC 0.567, 0.476 0.780, 1.51e−19 0.840, 1.75e−45
Immunosuppressive agents AUC 0.721, 1.43e−04 0.823, 6.36e−22 0.828, 9.44e−41
Neutropenia AUC 0.689, 5.60e−02 0.800, 7.68e−10 0.836, 1.11e−19
Immunity deficiency AUC 0.889, 4.06e−09 0.818, 3.26e−19 0.821, 9.74e−33
Anemia AUC 0.637, 9.75e−02 0.698, 3.13e−08 0.789, 1.40e−32
Hypertensive renal disease AUC 0.715, 1.35e−04 0.688, 6.74e−10 0.801,1.45e−42
End-stage renal failure AUC 0.677, 1.80e−03 0.868, 2.51e−29 0.898, 5.46e−72

Predictive accuracy (R2 and AUC) for MRS trained within only Latino/Hispanic- or white-non-Latino/Hispanic-identifying individuals compared to the accuracy trained on the entire, cross-ethnic cohort.