Table 3.

Model predictive performance metrics.

Years before T0	Sensitivity	Specificity	Accuracy	PPV	NPV
0	91.42	97.16	93.04	21.22	99.93
0.5	80.22	97.63	90.34	22.07	99.83
1	68.79	98.18	84.83	24.02	99.73
1.5	55.00	98.51	78.79	23.59	99.62
2	44.76	98.95	73.03	26.29	99.54
2.5	35.64	99.36	68.62	31.78	99.46
3	26.48	99.49	61.81	30.28	99.39
3.5	23.20	99.65	59.85	35.67	99.36

For all PPV and NPV calculation the prevalence was fixed at 0.83% (overall data set prevalence).