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. 2022 Aug 12;13:939311. doi: 10.3389/fimmu.2022.939311

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Copyright © 2022 Hua, Zhang, Yao, Xu, Sun, Lu, Xu, Liao, Yang, Mao, Zhang, Zhu, Hu, Lv and Jiang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Study processes for the two participant cohorts. Eligible participants were enrolled to receive two doses of CoronaVac on day 0 and day 28 (Cohort 1). After phase 1 recruitment, participants completed the two-dose immunization with Covilo were recruited (Cohort 2). Blood samples were collected and tested at Day 0, Day 28, Day 56 and Day 210 for Cohort 1 participants, while at Day 56 and Day 210 for Cohort 2 participants.