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. 2021 Apr 12;106(9):1288–1294. doi: 10.1136/bjophthalmol-2020-318672

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Exemplary case of a patient with subretinal pigment epithelial (sub-RPE) fluid at baseline (BSL) (D) and in historical imaging up to 11 months (A–C) before switch to brolucizumab as demonstrated in (from left to right) near-infrared imaging, spectral-domain optical coherence tomography through the fovea and colour-coded two-dimensional thickness map for total retinal thickness. At visit 1 (E), complete resolution of sub-RPE fluid was detected. Note: Before switch to brolucizumab, the patient received repetitive, high-frequency intravitreal injections of other anti-vascular endothelial growth factor agents over a longer period of time.