Table 4.

NDE, NIE, TE and proportion mediated for persistent asthma compared with never by socioeconomic circumstance (N=7487)

Blocks of mediators	Effects	OR	95% CI	Proportion mediated %	95% CI
Perinatal characteristics	NDE	1.43	0.72 to 2.84	37.5	30.6 to 43.3
	NIE	1.18	0.98 to 1.42
	TE	1.70	1.20 to 2.40
+Home environment at 3 years	NDE	1.26	0.63 to 2.50	61.2	56.0 to 65.4
	NIE	1.32	1.03 to 1.70
	TE	1.70	1.20 to 2.40
+Exposure to infection at 3 years	NDE	1.29	0.64 to 2.63	56.1	50.2 to 60.9
	NIE	1.29	1.00 to 1.66
	TE	1.70	1.20 to 2.40
+Neighbourhood characteristics at 3 years	NDE	1.27	0.62 to 2.63	58.9	52.9 to 63.7
	NIE	1.31	1.04 to 1.65
	TE	1.70	1.20 to 2.40

NDE, natural direct effect; NIE, natural indirect effect; TE, total effect.