Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Nov 23;59(9):865–877. doi: 10.1136/jmedgenet-2020-107623

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Craniofacial features. (A) Composite images of 15 patients with mcEDS-CHST14 in their childhood patients versus in their adolescence−adulthood using the Face2Gene facial recognition technology. (B) The binary comparison using Face2Gene demonstrates a difference between the facial features of childhood and adolescence to adulthood (area under the curve (AUC)=0.945; p=0.016 and receiver operating characteristic: (ROC)). (C) Clinical photographs of craniofacial features. A blue square indicates a single patient. Regardless of age or sex, most patients share common craniofacial characteristics, including hypertelorism, downslanting and short palpebral fissures, short nose with hypoplastic columella and long philtrum. Several features changed from childhood to adolescence: facial shape changed from round to slender and elongated, while microretrognathia changed to a protruding jaw.