TABLE 2.
SNPs and INDELs with suggestive significance for total aldehydes, hexanal, and nonanal content.
| Types | Trait | Chromosome | Position (bp) | Alt/Ref | p-value | Candidate genes a |
|---|---|---|---|---|---|---|
| SNP | Total aldehydes | 3 | 16649616 | G/A | 1.34E-06 | HNRNPLL, ARHGEF33, GEMIN6, GALM, SRSF7, ATL2, SOS1, MORN2 |
| INDEL | Total aldehydes | 3 | 16618276 | TCA/T | 1.81E-05 | HNRNPLL, ARHGEF33, GEMIN6, GALM, EIF4A3, ALT2, SRSF7, SOS1, MORN2 |
| SNP | Total aldehydes | 3 | 17035928 | T/C | 1.72E-06 | TRMT6, MCM8, CRLS1, C3H1orf95, PARP1, CHGB, SHLD1 |
| INDEL | Total aldehydes | 3 | 17035183 | AT/T | 1.50E-06 | |
| SNP | Total aldehydes | 8 | 4774847 | G/A | 2.51E-06 | SUCO, PRKAB2, PLPP6, FAM78B, PRDX6, FASLG, TADA1 |
| SNP | Total aldehydes | 8 | 6703077 | G/A | 1.26E-06 | TOR3A, FAM20B, RALGPS2, ANGPTL1, ABL2 |
| INDEL | Total aldehydes | 8 | 4637578 | T/TG | 9.48E-06 | PRKAB2, REG4, HMGCS2, PLPP6, FAM78B, PRDX6, NOTCH2, TADA1, SEC22B |
| INDEL | Total aldehydes | 8 | 4829634 | A/AT | 1.10E-05 | SUCO, DNM3, FASLG, PIGC |
| SNP | Hexanal | 3 | 101376953 | A/G | 7.53E-08 | LAPTM4A, MATN3, WDR35, TTC32 |
| INDEL | Hexanal | 3 | 101539230 | TG/T | 1.63E-06 | SDC1, PUM2 |
| INDEL | Hexanal | 3 | 36279875 | CT/C | 3.25E-05 | RGS7, GREM2 |
| INDEL | Hexanal | 3 | 82837851 | A/ACTAT | 1.96E-05 | FAM135A, COL9A1 |
| INDEL | Hexanal | 8 | 5844087 | C/CA | 1.17E-06 | LRRC52, MGST3, ALDH9A1, UCK2, DARS2, NUF2, KLHL20, CENPL, TMCO1 |
| SNP | Hexanal | 8 | 5847470 | C/A | 1.14E-06 | |
| SNP | Nonanal | 23 | 2466221 | T/C | 9.31E-08 | TAF12, MTFR1L, MAN1C1, LDLRAP1, TMEM57, SYF2, YTHDF2, RHCE, ID3, RSRP1, GMEB1, TMEM50A |
| INDEL | Nonanal | 23 | 2467306 | G/GAC | 1.14E-06 | |
| SNP | Nonanal | 6 | 27634814 | T/C | 2.20E-06 | GPAM, TECTB, ZDHHC6, ACSL5, VTI1A |
| INDEL | Nonanal | 23 | 2994896 | C/CT | 3.02E-05 | PTPRU, MECR, SRSF4 |
a
Genes located within 100 kb upstream or downstream of the suggestively associated SNPs and INDELs.