Table 1.
Baseline characteristics of people living with HIV in Catalonia according to SARS-CoV-2 vaccine status (December 2020–July 2021).
| Overall Cohort (n = 14,942) | Vaccinated x (n = 9945) | Unvaccinated (n = 4997) | p Value | |
|---|---|---|---|---|
| Characteristic | n (%) | n (%) | n (%) | |
| Sex a | <0.001 | |||
| Male | 12257 (82.0) | 8271 (83.2) | 3986 (79.8) | |
| Female | 2684 (18.0) | 1673 (16.8) | 1011 (20.2) | |
| Missing | 1 (0.01) | 1 (0.01) | 0 (0) | |
| Age, median (IQR), y b | 46.4 (38.3–54.2) | 49.0 (41.4–55.8) | 40.8 (32.8–49.3) | <0.001 |
| Age category, y b | <0.001 | |||
| 16–39 | 4479 (30.0) | 2106 (21.2) | 2373 (47.5) | |
| 40–64 | 9593 (64.2) | 7124 (71.6) | 2469 (49.4) | |
| 65–74 | 678 (4.5) | 553 (5.6) | 125 (2.5) | |
| ≥75 | 192 (1.3) | 162 (1.6) | 30 (0.6) | |
| Country of origin c | <0.001 | |||
| Spain | 8808 (59.0) | 6409 (64.4) | 2399 (48.0) | |
| Outside Spain | 6132 (41.0) | 3535 (35.6) | 2597 (52.0) | |
| Unknown | 2 (0.01) | 1 (0.01) | 1 (0.02) | |
| Socioeconomic deprivation | ||||
| Least deprived | 7188 (48.1) | 4749 (47.8) | 2439 (48.8) | 0.52 |
| Mildly deprived | 2839 (19.0) | 1997 (20.1) | 842 (16.9) | |
| Most deprived | 4574 (30.6) | 2962 (29.8) | 1612 (32.3) | |
| Missing | 341 (2.3) | 237 (2.4) | 104 (2.1) | |
| HIV transmission route | <0.001 | |||
| PWID | 1727 (11.6) | 1200 (12.1) | 527 (10.6) | |
| MSM | 7835 (52.4) | 5281 (53.1) | 2554 (51.1) | |
| Male heterosexual | 2055 (13.8) | 1391 (14.0) | 664 (13.3) | |
| Female hetero/homo/bisexual | 2008 (13.4) | 1266 (12.7) | 742 (14.9) | |
| Other | 856 (5.7) | 534 (5.4) | 322 (6.4) | |
| Missing | 461 (3.1) | 273 (2.8) | 188 (3.8) | |
| CD4 count (cells/μL) category | <0.001 | |||
| <200 | 3069 (20.5) | 2051 (20.6) | 1018 (20.4) | |
| 200–349 | 1266 (8.5) | 802 (8.1) | 464 (9.3) | |
| 350–499 | 2066 (13.8) | 1341 (13.5) | 725 (14.5) | |
| ≥500 | 7833 (52.4) | 5425 (54.6) | 2408 (48.2) | |
| Missing | 708 (4.7) | 326 (3.3) | 382 (7.6) | |
| HIV-RNA | <0.001 | |||
| Detectable | 1476 (9.9) | 783 (7.9) | 693 (13.9) | |
| Undetectable | 11891 (79.6) | 8317 (83.6) | 3574 (71.5) | |
| Missing | 1575 (10.5) | 845 (8.5) | 730 (14.6) | |
| Number of comorbidities | <0.001 | |||
| 0 | 4849 (32.5) | 2735 (27.5) | 2114 (42.3) | |
| 1 | 3661 (24.5) | 2422 (24.4) | 1239 (24.8) | |
| 2 | 2596 (17.4) | 1878 (18.9) | 718 (14.4) | |
| 3 | 1602 (10.7) | 1201 (12.1) | 401 (8.0) | |
| ≥4 | 2234 (15.0) | 1709 (17.2) | 525 (10.5) | |
| Previous SARS-CoV-2 diagnosis | <0.001 | |||
| Yes | 1610 (10.8) | 878 (8.8) | 732 (14.7) | |
| No | 13332 (89.2) | 9067 (91.2) | 4265 (85.4) |
Abbreviations: PLWH, people living with HIV; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; IQR, interquartile range; PWID, people who inject drugs; MSM, men who have sex with men. a Sex at birth as registered in the health registries of the participating hospitals was used. One participant in the overall cohort had an unknown sex. b Age for all patients was as of December 1, 2020. c Country of origin was as indicated by the Public Data Analysis for Health Research and Innovation Program of Catalonia (PADRIS) recorded as Spanish or Non-Spanish. x ≥1 dose of SARS-CoV-2 vaccine.