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. 2022 Aug 22;14(8):1748. doi: 10.3390/pharmaceutics14081748

Table 1.

Main properties of native cyclodextrins (CDs). Created based on information from [34,41,42,43].

Cyclodextrins α-CD β-CD γ-CD
Properties
Number of glucopyranose units 6 7 8
Hydrogen donors 18 21 24
Hydrogen acceptors 30 35 40
Molecular weight (Da) 972 1135 1297
Internal diameter (nm) 0.47–0.53 0.60–0.65 0.75–0.83
Outer diameter (nm) 1.46 1.54 1.75
Height of torus (nm) 0.79 0.79 0.79
Internal volume (nm3) 0.174 0.262 0.427
Solubility in water (g/100 mL, 25 °C) 14.5 1.85 23.2
Water of hydration (wt %) 10.2 13.2–14.5 8.13–17.7
Number of water molecules taken by cavity 6 11 17