Table 2.

BBB designs factors and Observed responses for Qu-PMMs.

Run	A	B	C	Y1	Y2	Y3
1	20	0.5	0.3	187.700 ± 8.654	0.398 ± 0.057	79.800 ± 0.721
2	20	0.1	0.2	107.167 ± 1.069	0.236 ± 0.053	77.460 ± 1.945
3	15	0.5	0.2	228.400 ± 8.190	0.296 ± 0.055	57.000 ± 1.952
4	20	1.0	0.2	192.320 ± 5.155	0.269 ± 0.014	59.920 ± 2.316
5	15	1.0	0.3	385.030 ± 6.615	0.330 ± 0.025	80.370 ± 1.316
6	15	0.5	0.2	231.730 ± 5.139	0.283 ± 0.044	55.610 ± 1.561
7	10	1.0	0.2	184.100 ± 3.820	0.264 ± 0.020	60.620 ± 1.660
8	15	0.1	0.1	541.560 ± 0.252	0.803 ± 0.055	55.550 ± 0.547
9	20	0.5	0.1	158.730 ± 5.519	0.345 ± 0.019	43.670 ± 0.846
10	15	0.5	0.2	228.400 ± 8.190	0.289 ± 0.046	76.330 ± 1.030
11	15	0.1	0.3	194.500 ± 1.706	0.393 ± 0.020	64.260 ± 0.981
12	15	1.0	0.1	299.430 ± 5.123	0.648 ± 0.021	72.310 ± 0.993
13	10	0.5	0.1	294.500 ± 1.706	0.393 ± 0.020	41.980 ± 1.547
14	10	0.1	0.2	321.960 ± 0.252	0.364 ± 0.020	37.280 ± 3.268
15	10	0.5	0.3	441.560 ± 9.075	0.397 ± 0.043	43.670 ± 0.846
16	15	0.5	0.2	225.060 ± 10.696	0.273 ± 0.011	58.000 ± 2.157
17	15	0.5	0.2	226.730 ± 9.078	0.281 ± 0.020	57.330 ± 2.521

A = Soluplus (mg mL⁻¹), B = E-TPGS (mg mL⁻¹), C = poloxamer 407 (% w/v), Y1 = Particle size (nm), Y2 = PDI and Y3 = Entrapment Efficiency (%). Data are represented in means ± Standard deviation (n = 3).