Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jul 30;14(8):1589. doi: 10.3390/pharmaceutics14081589

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Schematic of sHDL-Dox for chemo-immunotherapy. (A) Schematic of the lipid-DOX conjugate and the preparation process. (B) The image of sHDL-DOX using a transmission electron microscope. Scale bars, 50 nm. (C) The release of DOX at pH 5 and pH 7.5. Data represent mean ± SD (n = 3). (D) Schematic of sHDL-DOX triggering antigen release for cancer immunotherapy. (E) The increased percentage of IFN-γ + CD8+ T cells induced by sHDL-DOX. (F) The increased percentage of CT26 tumor antigen peptide AH1-specific CD8+ T cells induced by sHDL-DOX. Reprinted with permission from Ref. [123]. Copyright 2018, copyright the American Association for the Advancement of Science.