Table 4.
Subgroup analysis of persons with viral load > 200 copies/ml after the initiation on ART
| Parameter | Persistent viraemia group (n = 15) (Naïve) | Persistent viraemia group (n = 15) (ART) | p value |
|---|---|---|---|
| CD4 count (cells/μl) | 277 (214–355) | 388 (209 to 529) | 0.01 |
| CD8 count (cells/μl) | 980 (774–1536) | 671 (465 to 1018) | 0.009 |
| HIV viral load (copies/ml) | 77 005 (7478–350 082) | 2389 (20 to 89 339) | 0.005 |
| HIV viral load (log copies/ml) | 4.9 (3.9–5.5) | 3.4 (1.3*–5.0) | 0.001 |
| Presence of pericardial effusion | 10 (67%) | 11 (73%) | 0.7 |
| LA diameter (mm) | 31 ± 5 | 32 ± 4 | 0.1 |
| LA area (cm2) | 19 ± 3 | 20 ± 3 | 0.2 |
| RA area (cm2) | 18 ± 4 | 19 ± 3 | 0.1 |
| LV end diastolic volume (ml) | 132 ± 30 | 137 ± 27 | 0.5 |
| LV end diastolic volume indexed to body surface area (ml/m2) | 81 ± 16 | 81 ± 14 | 1.0 |
| RV end diastolic volume indexed to body surface area (ml/m2) | 79 ± 17 | 78 ± 11 | 0.6 |
| RV end diastolic volume (ml) | 127 ± 28 | 132 ± 24 | 0.7 |
| LV mass (g) | 84 (74 to 128) | 94 (79 to 117) | 0.02 |
| LV mass indexed to body surface area (g/m2) | 59 (50 to 65) | 60 (53 to 70) | 0.02 |
| LV ejection fraction (%) | 59 ± 5 | 59 ± 5 | 0.2 |
| LV stroke volume (ml) | 79 ± 18 | 82 ± 16 | 0.1 |
| RV ejection fraction (%) | 60 ± 5 | 61 ± 5 | 0.1 |
| RV stroke volume (ml) | 78 ± 17 | 81 ± 15 | 0.3 |
LV left ventricle, RV right ventricle, LA left atrial, RA right atrial
*20 copies/ml (log = 1.3) is the lower limit of measurement for our HIV-1 assay
Bold values indicates p value < or = 0.05