Skip to main content
. 2022 Aug 12;15(8):994. doi: 10.3390/ph15080994
Multiple sclerosis MS
Central nervous system CNS
Myelin oligodendrocyte glycoprotein MOG
Dendritic cells DC
Matrix metalloproteinase MMP
Blood–brain barrier BBB
T helper Th
Integrin ITG or IT
Integrin alpha 4 subunit ITGA4, ITA4, or CD49d
Integrin beta 1 subunit ITGB1, ITB1, or CD29
Integrin alpha 4 subunit and integrin beta 1 subunit form α4β1 dimer or very late antigen-4 (VLA-4)
Vascular cell adhesion protein VCAM-1
Simplified molecular-input line-entry system SMILE
Absorption, distribution, metabolism, and excretion parameters ADME
Topological polar surface area TPSA
Molecular weight MW
Split-intein circular ligation of peptides and proteins SICLOPPS
G protein-coupled receptors GPCRs
Post-translational modifications PTMs
Melanocortin receptor family MCR
Root-mean-square deviation RMSD
Accessible surface area SASA
IDSP motif Ile-Asp-Ser-Pro
Drug–target interaction DTI
Extracellular matrix ECM
Tissue inhibitor of matrix metalloproteinase TIMP
Vinculin VCL
Protein tyrosine kinase 2 beta PTK2B
Inside-out signaling pathway regulator of kinases protein CRK
Cytosolic tyrosine kinase that negatively regulates Src family kinases CSK
Adapter protein, which links cell–cell and cell–matrix adhesions to an extended signaling network BCAR1
Mammalian isoforms of talin TLN1
Src family protein tyrosine kinases member SRC
Glycoprotein in the ECM fibronectin FN1
Addressin mucosal addressin cell adhesion molecule-1 MAdCAM-1
Individual database ID
Protein Data Bank PDB
Molecular dynamics MD
Protein–protein interaction PPI
Food and Drug Administration FDA
Osteopontin OPN