Table 2.
Weights and blood pressure in offspring at 12 weeks of age.
| Groups | C | CKD | CP | CKDP |
|---|---|---|---|---|
| Mortality | 0% | 0% | 0% | 0% |
| Body weight (BW) (g) | 281 ± 8 a | 304 ± 18 a | 319 ± 11 a | 269 ± 7 b |
| Left kidney weight (KW) (g) | 1.31 ± 0.05 b | 1.62 ± 0.08 a | 1.40 ± 0.05 b | 1.33 ± 0.06 b |
| Left KW/100 g BW | 0.47 ± 0.01 | 0.55 ± 0.05 | 0.4 ± 0.01 | 0.49 ± 0.01 |
| Systolic BP (mmHg) | 132 ± 1 b | 144 ± 1 a | 133 ± 1 b | 135 ± 1 b |
| Diastolic BP (mmHg) | 87 ± 2 | 95 ± 2 | 86 ± 2 | 91 ± 1 |
| Mean arterial pressure (mmHg) | 102 ± 1 b | 112 ± 2 a | 101 ± 1 b | 106 ± 1 b |
N = 7–8/group; the letters a and b denote significant differences between groups (p < 0.05, one-way ANOVA). BP = blood pressure. C = control; CKD = adenine-treated rats; CP = control rats received propionate; CKDP = adenine-treated rats received propionate.