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Roughness effect on PC formation. SEM images of (a) virus-like silica nanoparticles (VSN) and (e) wrinkled silica nanoparticles (WSN). Multicolor STED images and line profiles of coverslip-immobilized. (b, c) VSN and (f, g) WSN. STED images have a pixel size of 20 nm. (d, h) Histograms of protein contents of all three proteins from protein corona coated on single VSN and WSN nanoparticles.
