Table 2.
Solicited local and systemic reactions to the ChAdOx1 nCoV-19 vaccine reported 0 to 7 days after vaccination in hemodialysis patients according to their anti-spike IgG antibody response at day 28.
| Variables | All (n = 206) | Nonresponders (n = 68) | Responders (n = 138) |
p Value |
|---|---|---|---|---|
| Any local reaction, n (%) | 80 (38.8%) | 18 (26.5%) | 62 (44.9%) | 0.011 |
| Pain, n (%) | 77 (37.4%) | 18 (26.5%)) | 59 (42.8%) | 0.023 |
| Redness, n (%) | 19 (9.2%) | 4 (5.9%) | 15 (10.9%) | 0.245 |
| Swelling, n (%) | 25 (12.1%) | 5 (7.4%) | 20 (14.5%) | 0.140 |
| Any systemic reaction, n (%) | 119 (57.8%) | 31 (45.6%) | 88 (63.8%) | 0.013 |
| Fatigue, n (%) | 62 (30.1%) | 15 (22.1%) | 47 (34.1%) | 0.077 |
| Headache, n (%) | 34 (16.5%) | 7 (10.3%) | 27 (19.6%) | 0.092 |
| Muscle and joint pain, n (%) | 47 (22.8%) | 9 (13.2%) | 38 (27.5%) | 0.021 |
| Nausea or vomiting, n (%) | 4 (1.9%) | 1 (1.5%) | 3(2.2%) | 0.073 |
| Abdominal pain, n (%) | 11 (5.3%) | 3 (4.4%) | 8 (5.8%) | 0.677 |
| Diarrhea, n (%) | 14 (6.8%) | 2 (2.9%) | 12 (8.7%) | 0.123 |
| Fever, n (%) | 60 (29.1%) | 11 (16.2%) | 49 (35.5%) | 0.004 |
| Symptom score a | 1.0 (0.0–3.0) | 1.0 (0.0–1.0) | 1.0 (0.0–3.0) | 0.002 |
a A score of one was awarded for every local and systemic reaction reported, and then the total symptom score was calculated for each participant (maximum 10 points out of 10).