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. 2022 Aug 9;14(8):1658. doi: 10.3390/pharmaceutics14081658

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PET images were obtained with [¹¹C]domperidone and [¹¹C]metoclopramide after selected doses of the P-gp inhibitor tariquidar (TQD). Representative PET images are summed from 0 to 30 min and were obtained at baseline and after P-gp inhibition (8 mg/kg TQD for [¹¹C]metoclopramide and 15 mg/kg TQD for [¹¹C]domperidone).