TABLE 2.
A summary of the morphological characteristics of melanopsin ganglion cell types in the mouse retina
| Type | Soma size (μm; mean ± SEM) | Dendritic field size (μm; mean ± SEM)a | Branch points (mean ± SEM) | Sample size (n =?) |
|---|---|---|---|---|
| M1 | 15.7 ± 0.5 | 347.9 ± 19.7 | 10.2 ± 1.6 | 254 (s), 259 (d) |
| M2 | 18.2 ± 0.6 | 383.8 ± 18.0 | 19.4 ± 1.9 | 183 (s), 182 (d) |
| M3 | 16.3 ± 1.2 | 463.2 ± 27.4 | Undetermined | 19 |
| M4 (n) | 24.2 ± 1.5 | 371.9 ± 22.7 | 34.5 ± 2.8 | 54 |
| M4 (t) | 21.3 ± 0.7 | 207.6 ± 6.9 | 30.4 ± 1.5 | 18 |
| M5 | 14.2 ± 0.4 | 224 ± 6.6 | 52.1 ± 1.9 | 47 |
| M6 | 12.7 ± 0.3 | 216 ± 5.1 | 100 ± 4.6 | 34 |
Note: Values are mean ± SEM and were calculated using reported values from the papers in Table 1 (Berson et al., 2010; Ecker et al., 2010; Estevez et al., 2012; Muller et al., 2010; Quattrochi et al., 2019; Schmidt et al., 2014; Schmidt & Kofuji, 2009, 2011; Sonoda et al., 2019; Stabio, Sabbah, et al., 2018).
It should be noted that the dendritic field size for M4 cells differs based on retinal location, with M4 cells located in the nasal retina having a larger dendritic field than M4 cells located in the temporal retina (Bleckert, Schwartz, Turner, Rieke, & Wong, 2014; Sonoda et al., 2019). M4 (n) = M4 cells located in the nasal retina; M4 (t) = M4 cells located in the temporal retina.