Table 4.
The relationship between each parameter, the HMGB-1 concentration at the inlet side (CBi), hemofilter type, and time, and the interaction between the CBi and hemofilter type, with the HMGB-1 CL as an objective variable, using a linear mixed model. *: p-value of <0.05 was considered as significant.
| After the Initial Addition | Coefficient (β) | 95%LCI | 95%UCI | p-Value | |
|---|---|---|---|---|---|
| (a) | HMGB-1 concentration at the inlet side (CBi) |
0.166 | −0.053 | 0.351 | 0.102 |
| Hemofilter type | −3.452 | −8.497 | 1.206 | 0.175 | |
| Time | −0.069 | −0.110 | −0.034 | 0.001 * | |
| Interaction between CBi and hemofilter type |
0.269 | 0.108 | 0.441 | 0.003 * | |
| After the Re-Addition | Coefficient ( β) | 95%LCI | 95%UCI | p -Value | |
| (b) | HMGB-1 concentration at the inlet side (CBi) |
0.044 | −0.125 | 0.246 | 0.623 |
| Hemofilter type | −2.951 | −9.960 | 4.057 | 0.430 | |
| Time | −0.020 | −0.062 | 0.027 | 0.361 | |
| Interaction between CBi and hemofilter type |
0.121 | −0.044 | 0.286 | 0.173 |