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. 2022 Jul 30;15(8):950. doi: 10.3390/ph15080950

Scheme 1.

Scheme 1

Synthesis of the curcumin analogs A1A8. Reagents and conditions: (a) SOCl2, 80 °C, reflux, 2 h; (b) CHCl3, triethylamine, 0 °C to room temperature, 12 h.